Anticonvulsant drug promising as a treatment for cocaine abuse
CONTACT: Blair Gately Michelle Person 301-443-6245 Espaol Contact: Sara Rosario 301-594-6145 National Institute of Health (USA) in a preliminary clinical trial funded by the National Institute on Drug Abuse, National Institutes Health, suggests that gamma vinyl -GABA (GVG), a drug used to treat epilepsy may offer a potentially effective treatment for cocaine addiction. Researchers at New York University School of Medicine and Brookhaven National Laboratory in Upton, New York, the report this week in the online version of the journal Synapse that a small trial, preliminary clinical study in Mexico found the drug could reduce cocaine use dramatically people who have used cocaine daily for at least 3 years.The data in this study reported the need for a larger, double-blind,
placebo-controlled disadvantages confirm the efficacy and safety of this drug to determine for cocaine addiction, say the authors. GVG reduced dopamine, a chemical well-being that floods the brains of cocaine users, providing high it needs, says Dr. Frank Vocca, Director, Division of Treatment Research and Development, National Institute on Drug Abuse. With GVG, the dopamine system may effectively block the effects of cocaine addiction is temperament.A total of 19 men and one woman entered the study. Eight people completed the study who received increasing doses of GVG in the first week until you reach the maximum dose of 4 grams per day. At that time, he was writing the article, these eight people had been drug free for 4658 days, said Dr. Jonathan Brodie, the Marvin
Stern Professor of Psychiatry at New York University and author of the study. All eight of these subjects have remained clean despite no longer on GVG and have indicated that greed is not returned for at least 4 weeks, he added.Therefore, they have all been drug free for at least 74 days and counting.This preliminary finding has important implications for our drug development program, says NIDA Director Dr. Nora D.
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