Brain immune system triggered in autism
A Johns Hopkins study is further evidence that the brains of some people with autism show clear signs of inflammation, suggesting that the disease to the brain activation of the immune system is attached. These results support the hypothesis that the immune response in the brain is involved in autism, although it is unclear whether inflammation is a consequence of a disease or a cause, or both, said Carlos Pardo-Villamizar, MDonline in the journal Annals of Neurology, November 15. Whatever the cause of inflammation, can provide a good target for developing new treatments, says Pardo. Autism is a brain development disorder that appears in early childhood. According to the American Neurological Association, which is estimated to affect between two and five of every 1,000
children and is four times more likely to strike boys than girls.Behaviors and rare plants, objects or routines. Autism is a strong genetic component in some families, but other causes may play a role, perhaps even at birth complications, diet, toxins or infections, said Pardo. Scientists have found evidence that the immune system may be involved in autism, but not all studies have confirmed this, said Pardo. We have a more precise answer was, well, instead of the immune system, we we have focused on immune responses within the nervous system relatively closed.
Led by first author Diana L. Vargas, MD, a postdoctoral fellow in the laboratory of Brown, the researchers examined tissue from three different regions of the brain in 11 persons with autism, aged 5 to 44, who
died from accidents or injuries . They also measured levels of two immune system proteins called cytokines and chemokines, found in the cerebrospinal fluid - the clear substance that surrounds, bathes and nourishes the brain and spinal cord - in six patients living with autism , ages 5 to 12 years.Compared with normal control brains, the brains of people with autism show signs of an ongoing inflammatory process in
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